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Levodopa is given orally and in order to maximize the amount that actually reaches the brain, it is given in combination with a decarboxylase inhibitor, carbidopa, cheap phentermine hcl does not enter the brain. Because the drug is not converted into dopamine outside of the brain, this greatly increases the effective dose of levodopa and reduces peripheral side effects. This combination seems to be the best treatment for most Parkinsons patients, at least in the early stages. The site of decarboxylation of levodopa in patients with Parkinsons disease is uncertain, but it may be that there is sufficient enzyme in the remaining dopamine nerve terminals or that conversion takes place in other neurons as they also contain decarboxylase enzymes. Release of dopamine replaced in this way must be very abnormal but most patients seem to benefit.

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Post-encephalitic Parkinsonism followed an epidemic of viral encephalitis between Drug-induced Parkinsonism can occur as an adverse effect to drugs used to treat psychotic disorders. In the cheap phentermine hcl paralysis. The cause was found to be a contaminant called methylphenyltetrahydropyridine (MPTP), which causes severe degeneration of the nigrostriatal tract. This led to the suggestion that idiopathic Parkinsons disease may be caused by some, as yet, unidentified neurotoxin.