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Typically the first metatarsal-phalangeal joint of the big toe is affected, although the finger joints and the joint at the base of the thumb may also be involved. An episode of gout can be triggered by excessive alcohol consumption, a diet high in purines, surgery, sudden severe illness, injury to a joint, use of diuretics or chemotherapy. Over several years, uric acid crystals can build up in other tissues to form large deposits, called tophiunder the skin. Tophi are often found in or near severely affected joints, on or near the elbow, over the fingers and toes and in the outer edge of the ear.
Authored by Dr. Donovan Patrick Stewart, DC