Pharmacologic treatments for refractory warts, including cimetidine, have been used with varied success. Recurrences are common and may be attributable to reactivation rather than reinfection. Sexually active female adolescents who have had an organ transplant or are receiving long-term corticosteroid therapy also should undergo similar cervical Pap test screening. If cytologic screening has been initiated before 21 years of age, patients with abnormal Pap test results should be cared for by a physician who is knowledgeable in the management of cervical dysplasia. Intralesional interferon, indolecarbinole, photodynamic therapy, and intralesional cidofovir have been used as investigational treatments and may be of beneft for patients with frequent recurrences. Oral warts can be removed through cryotherapy, electrocautery, or surgical excision. In addition, use of latex condoms has been associated with a decrease in the risk of genital warts and 1 American College of Obstetricians and Gynecologists.
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