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<p>Decapeptyl SR injection is a hormone treatment that has different uses in men, women and children. In men, Decapeptyl injections are given to treat prostate cancer.</p>
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<p>Very few direct comparative studies between GnRH agonists and antagonists were identified. For a summary of these data, see Table 7. Use of triptorelin prior to prostatectomy resulted in a lower rate than the control group, but there was no effect on progression-free survival 96 — 97. The testosterone response rates were comparable at one year. Testosterone levels decreased more rapidly in the degarelix arm than in the goserelin arm, at eight weeks the levels were similar 11.</p>
<p>There are almost no known interactions with any of the GnRH agonists. The clinical efficacy of goserelin and leuprorelin are much better documented than the other drugs. In this article the SOJA method was applied to both GnRH agonists and antagonists in order to make a transparent and rational selection of the most suitable medicines. Efficacy Improved overall survival should be the aim or all cancer treatment but this requires very large scale and long-term studies to establish.</p>
<p>In The Netherlands, many expensive drugs will be transferred to the hospital budget in January We have not included the criterion acquisition cost, to allow for a pre-selection only on quality aspects. More special precautions are applicable to abarelix and degarelix. The duration and size of most studies was insufficient to make firm statements concerning relative safety in the long term. No differences were found in the first two studies, a longer time to progression was found for goserelin compared to cyproterone acetate 78.</p>
<p>Documentation The score for this criterion is divided into four sub-criteria: 1 number of randomized comparative studies; 2 number of patients in these studies; 3 number of years marketed; and 4 number of patient days worldwide. The dosage frequency of the agonists is more favourable than the antagonists. Androgens stimulate the growth of both normal and cancerous prostate cells. The effects casodex decapeptyl 3mg time to progression and survival were similar 16.</p>
<p>A higher overall survival was seen compared to radiotherapy alone 81. About 8, new patients are diagnosed with prostate cancer in The Netherlands each year 2. The effects on testosterone were identical. Another study compared intermittent and continuous ADT 62. Scores for different dosage frequecies are given in Table 4. PSA was reduced compared to surgery alone.</p>

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