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Indomethacin is primarily used as part of a long-term treatment plan in people with rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Indomethacin prevents the synthesis of prostaglandin, a compound involved in the inflammatory response in the body and one which is thought to make the nerves more sensitive. Indomethacin for gout management is sometimes used along with allopurinol, colchicine and probenecid. Indomethacin is cheap indocin bound to proteins in the plasma and can cross the placenta as well as the blood-brain barrier. The half-life of indomethacin is approximately 4. Indomethacin's side effects include stomach pain, nausea, vomiting, chest pain, shortness of breath, and rash.
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It is also used to treat bursitis, tendinitis acute painful shoulder, acute gouty arthritis, and other kinds of pain. Most important fact about this drug You should have frequent checkups with your doctor if you take Indocin regularly. Ulcers or internal bleeding can occur without warning. How should you take this medication? Indocin should be taken with food or an antacid, and with a full glass of water.