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Olmesartan belongs to the angiotensin II receptor blocker ARB family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 AT1 and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, benicar tablet 40 mg and synthesis of aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. Overall, olmesartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced cardiac activity, and increased excretion of sodium. Olmesartan also affects the renin-angiotensin aldosterone system RAAS, which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions.

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For adults and children aged 6 years and over, the usual starting dose is 10mg taken once a day. Children weighing less than 35kg about 5. After a few weeks your doctor will check your blood pressure and ask you if you're getting any side effects.

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