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Synopsis: Desloratadine Clarinex is the orally active metabolite of the nonsedating histamine-1 H 1 receptor antagonist loratadine Claritin. It is indicated for seasonal and perennial allergic rhinitis and chronic idiopathic urticaria in patients 12 years of age and older. Safety: There are no major safety issues associated with desloratadine. Desloratadine is category C in pregnancy, and passes through the milk during breastfeeding. Tolerability: Desloratadine is well tolerated. The type and number of side effects associated with desloratadine are similar to those associated with placebo. The most common adverse events are headache, fatigue, and dry mouth, which occur in 2 to 3 percent of people.
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