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Desloratadine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Desloratadine is used to treat the symptoms of allergies, such as sneezing, watery eyes, and runny nose. You should not take this medication if you are allergic to desloratadine or to loratadine Claritin. Before taking desloratadine, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.

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