They do not treat viral infections e. When CLEOCIN HCl is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may. Its use should be reserved for penicillin -allergic patients or other patients for whom, in the judgment of the physician, a penicillin is inappropriate. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. Infections and Infestations: Clostridium difficile colitis. Vesiculobullous rashes, as well as urticaria, have been observed during drug therapy.

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Avoid IM injections in patients receiving anticoagulant therapy; administer PO in these circumstances; in general, administer IV only if patient does not tolerate or is unable to absorp oral medications. C difficile produces toxins A and B, which contribute to CDAD; hypertoxin-producing C difficile strains increase morbidity and mortality more likely to be refractory to antimicrobial therapy and may require colectomy. If CDAD suspected or confirmed, ongoing antibiotic use not directed against C difficile may need to be discontinued. Risk of potentially fatal pseudomembranous colitis, fungal or bacterial superinfection on prolonged use; discontinue therapy if significant abdominal cramps, diarrhea, or passage of blood and mucus occurs. May increase risk of drug-resistant bacteria if prescribed in the absence of proven or strongly suspected bacterial infection. Use caution in hepatic impairment, monitor for hepatic abnormalities; periodic liver enzyme determinations should be made when treating patients with severe liver disease. Serious anaphylactic reactions require immediate emergency treatment with epinephrine; oxygen and intravenous corticosteroids should also be administered as indicated. Discontinue therapy permanently and institute appropriate therapy if anaphylactic or severe hypersensitivity reaction occurs. In clinical trials with pregnant women, systemic administration of clindamycin during the second and third trimesters, has not been associated with increased frequency of congenital abnormalities.

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Adolescents and Adults age 12 years and older Cellulitis - - mg twice a day or mg once daily for 10 days PI Sinusitis - - mg twice a day for 10 days PI Strep throat - mg once daily for 10 days PI. Suspension and tablet are not bioequivalent on a mg-to-mg basis. Adults and Adolescents Age 13 years and older Pneumonia, community-acquired - mg twice a day for 10 days PI Sinusitis - mg twice a day or mg once daily for 10 days IDSA Skin infections - mg twice a day for 10 days PI Strep throat - mg twice a day for 5 - 10 days or mg once daily for 10 days PI Urinary tract infection - mg twice a day for 3 - 7 days IDSA. Do not take within 2 hours of each other. Adults and Adolescents Age 12 years and older Pneumonia, community-acquired - mg twice a day for 14 days PI Skin infections - mg twice a day for 10 days PI Strep throat - mg twice a day for 10 days PI. Cefditoren has been discontinued in the U.

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