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Today, Merck's cholesterol-lowering drug Zocor loses its United States patent protection, becoming the largest-selling drug yet to be opened to cheap generic competition. That change will cost Merck billions of dollars a year. Now insurers are hoping to convince patients price omnicef doctors that cheap clones of Zocor will make full-priced Lipitor an unnecessary luxury. But beginning today, three other drug companies will be legally allowed to sell simvastatin, the active ingredient in Zocor. As a result, the price of a dose of simvastatin will probably drop 30 percent or more in the next few days, and by as much as 90 percent next year, to about 30 cents a pill.
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Whitehouse Station, NJ - Merck's blockbuster cholesterol-lowering agent, Zocor simvastatin, loses its US patent protection tomorrow, when the first generic competitors will appear. This move is expected to have a big impact on the statin market, affecting sales of not just Zocor but also the other major branded statins, L ipitor atorvastatin, and Crestor rosuvastatin, AstraZeneca. The statin market is currently dominated by Lipitor, with Zocor in second place. Although sales of Zocor will undoubtedly be slashed by generic competition, Lipitor is also likely to suffer. While the highest dose of atorvastatin is more potent than simvastatin, it has been estimated that most patients can reach target LDL-cholesterol goals with simvastatin, and this is bound to encourage insurers to insist patients switch to this cheaper alternative. When the patent protection expires on a drug, the first company to file for a generic usually gets six months of market exclusivity, so generic competition is limited to start with.