Sildenafil is used in the treatment of Erectile Dysfunction. Sildenafil excretion from the body is reduced by some medicines like erythromycin and cimetadine Inhibitors of CYP3A4 enzyme in liver so its effect or side effects may last longer in patients taking these medicines. Rifampicin may decrease the plasma concentrations of sildenafil. Symptomatic hypotension may occur when sildenafil is used along with beta lockers. Plasma concentrations of sildenafil is increased by ritonavir.
This medication is a phosphodiesterase type 5 PDE5 inhibitor, prescribed for erectile dysfunction impotence. It can also be used in pulmonary arterial hypertension. Adjust dose based on response. Max: mgdose and not more than once in 24 hour. Pulmonary Arterial Hypertension- 20 mg 3 times daily.
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