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Is Alli — an over-the-counter weight-loss pill — the solution to your weight-loss woes? Alli pronounced AL-eye is an over-the-counter drug meant for overweight adults struggling to shed excess pounds. Both Alli and Xenical are meant to be used as part of a weight-loss plan, along with a low-calorie, low-fat diet and regular physical activity. Food and Drug Administration for use in adults 18 and older who have a body mass index BMI of 25 or more. Xenical is approved for use in adults with a BMI of 30 or more obese.

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