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Patients per 1, population dispensed at least 20 tablets of zopiclone in the 12 months from October, to September, by ethnicity. However, in practice some clinicians use clonazepam to treat anxiety. It is a long-acting benzodiazepine; NZF does not list a dose for use in anxiety. Half-life is likely to be longer in older or frail patients, or those with renal impairment. The use of benzodiazepines with long half-lives is not recommended in older or frail patients. Lorazepam and diazepam are medium and long-acting benzodiazepines, respectively, indicated for the treatment of anxiety short-term use only, acute alcohol withdrawal, status epilepticus, muscle spasm and as sedatives during medical procedures.

In August, the supplier announced the discontinuation of oxazepam Ox-Pam, a short-acting benzodiazepine indicated for the treatment of anxiety and alcohol withdrawal. It is expected that supply of Ox-Pam will run out in July, Patients who are currently using oxazepam will need to switch to an alternative benzodiazepine, which then may be able to be slowly withdrawn.

Nitrazepam Nitrados, indicated for insomnia, has also been discontinued and was delisted from the Pharmaceutical Schedule on 1 January, No other brand of nitrazepam is being funded. Patients may be less willing to try other treatments that are not as instantly gratifying, such as non-medical interventions for insomnia or anxiety, but these are likely to be safer and more appropriate in the long-term.

In patients with severe symptoms, medicines may be used short-term while non-pharmacological measures are implemented. If a hypnotic is being considered, because other interventions have been unsuccessful, a short-acting preparation should be chosen i. Non-pharmacological strategies should be continued alongside, e. Prescribing benzodiazepines as a first-line treatment option, even for short-term benefit, can lead to patient reliance on the medicine for anxiety management, and may deter commitment to later psychological interventions due to the comparatively delayed symptom relief.

If prescribed, discuss these risks with patients and put in place a plan to minimise their occurrence, e. Benzodiazepines and zopiclone can cause a range of adverse effects, including: 2, 11, 5. These adverse effects can lead to adverse clinical outcomes, such as an increased risk of falls and motor vehicle accidents.

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